Author: Alt, D.M.
Paper Title Page
THPMP052 Recent Progress in R&D for Ionetix Ion-12SC Superconducting Cyclotron for Production of Medical Isotopes 3568
  • X. Wu, G.F. Blosser, G.S. Horner, Z.S. Neville, J.M. Paquette, N.R. Usher, J.J. Vincent
    Ionetix, Lansing, Michigan, USA
  • D.M. Alt
    NSCL, East Lansing, Michigan, USA
  The Ion-12SC is a sub-compact, 12.5 MeV proton su-perconducting isochronous cyclotron for commercial medical isotope production recently developed at Ionetix Corporation [1]. The machine features a patented cold steel and cryogen-free conduction cooling magnet, a low power internal cold-cathode PIG ion source, and an inter-nal liquid target [2]. It was initially designed to produce N-13 ammonia for dose on-demand cardiology applica-tions but can also be used to produce F-18, Ga-68 and other medical isotopes widely used in Positron Emission Tomography (PET). The 1st engineering prototype was completed and commissioned in September 2015, and four additional units have been completed since [3]. The first two units have been installed and operated at the University of Michigan and MIT. R&D efforts in physics and engineering have continued to improve machine performance, stability and reliability. These improve-ments include: 1) Water cooling added to the dummy dee to limit the operating temperature of the ion source to improve lifetime and performance, 2) Magnetic field maps, obtained with a Hall probe based mapper, were used to accurately measure the isochronism and provide information needed to compensate for any unwanted 1st harmonics and 3) Feedback based control methods ap-plied to regulate the beam intensity on target by adjusting the ion source cathode current. The C1 unit installed at the University of Michigan Medical School early this year treated ~100 patients/month with N-13 ammonia. The machines are now capable of routinely producing > 21 doses/day with > 99% availability. The Ionetix manu-facturing facility is capable of producing up to 30 ma-chines per year.  
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About • paper received ※ 14 May 2019       paper accepted ※ 22 May 2019       issue date ※ 21 June 2019  
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